Plicamycin FDA Link

A tricyclic pentaglycosidic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA. It is used as a fluorescent dye and as an antineoplastic agent, especially in bone and testicular tumors. Plicamycin is also used to reduce hypercalcemia, especially that due to malignancies.

Also Known As:

Mitramycin; Aureolic Acid; Mithramycin

Pharmalogical Action Categories:

Antibiotics, Antineoplastic
Fluorescent Dyes
Nucleic Acid Synthesis Inhibitors
Protein Synthesis Inhibitors

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthacenes
        Anthracyclines: 9423
        Plicamycin: 291
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthacenes
    - Anthracyclines: 9423
      - Plicamycin: 291
Carbohydrates: 22023
- Glycosides: 2119
  - Aminoglycosides: 5131
    - Anthracyclines: 9423
      - Plicamycin: 291

bis(mithromycin)iron(II)

Bio-Agent Context: Research Results