Xeroderma Pigmentosum Group D Protein

A DNA helicase that is a component of TRANSCRIPTION FACTOR TFIIH. It plays an essential role in NUCLEOTIDE EXCISION REPAIR, and mutations in this protein are associated with XERODERMA PIGMENTOSUM.

Also Known As:

ERCC2 Protein; Excision Repair Cross-Complementing Rodent Repair Deficiency, Group 2 Protein; Xeroderma Pigmentosum Complementation Group D Protein; Excision Repair Cross Complementing Rodent Repair Deficiency, Group 2 Protein

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Acid Anhydride Hydrolases
      - Adenosine Triphosphatases: 8623
        DNA Helicases: 627
        Xeroderma Pigmentosum Group D Protein: 3
  - Isomerases: 463
    - DNA Helicases: 627
      - Xeroderma Pigmentosum Group D Protein: 3
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Transcription Factors: 38804
    - General Transcription Factors: 14
      - TFII Transcription Factors: 1
        Transcription Factor TFIIH: 77
        Xeroderma Pigmentosum Group D Protein: 3
  - DNA-Binding Proteins: 2009
    - General Transcription Factors: 14
      - TFII Transcription Factors: 1
        Transcription Factor TFIIH: 77
        Xeroderma Pigmentosum Group D Protein: 3

mouse Ercc2 protein

Bio-Agent Context: Research Results