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Xenopus naked cuticle protein

Wnt-induced antagonist found in this pathway, establishes a negative-feedback loop that limits the Wnt signal required for early segmentation; in addition, Naked cuticle is proposed to function as a switch, acting to restrict classical Wnt signaling and to activate a second Wnt signaling pathway that controls planar cell polarity during gastrulation movements
Also Known As:
naked cuticle protein, Xenopus; NKD protein, Xenopus
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Bio-Agent Context: Research Results