Inhibitor of Apoptosis Proteins

A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat; some members have ubiquitin-protein ligase activity.

Also Known As:

BIRC2 Protein; Baculoviral IAP Repeat Containing Protein 2; Baculoviral IAP Repeat-Containing 2 Protein; Baculoviral Inhibitor Of Apoptosis Repeat Proteins; Cellular Inhibitor of Apoptosis 1 Protein; IAP Protein (Apoptosis); IAP Repeat Containing Proteins; IAP2 Protein; Inhibitor of Apoptosis 2 Protein; Inhibitor-Of-Apoptosis Protein; c-IAP1 Protein; cIAP1 Protein; Apoptosis Proteins Inhibitor; Baculoviral IAP Repeat Containing 2 Protein; Inhibitor Of Apoptosis Protein

Pharmalogical Action Categories:

Caspase Inhibitors

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Ligases: 5553
    - Ubiquitin-Protein Ligase Complexes
      - Ubiquitin-Protein Ligases: 3432
        Inhibitor of Apoptosis Proteins: 717
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Apoptosis Regulatory Proteins: 2514
      - Inhibitor of Apoptosis Proteins: 717
- Peptides: 82426
  - Intracellular Signaling Peptides and Proteins: 32
    - Apoptosis Regulatory Proteins: 2514
      - Inhibitor of Apoptosis Proteins: 717

human XIAP protein

Bio-Agent Context: Research Results