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CJ 13610

structure in first source

Also Known As:

CJ-13,610

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - CJ 13610: 3
Inorganic Chemicals: 9
- Electrolytes: 16106
  - Ions: 7857
    - Anions: 3501
      - Sulfides: 1062
        CJ 13610: 3
- Sulfur Compounds: 278
  - Hydrogen Sulfide: 2764
    - Sulfides: 1062
      - CJ 13610: 3
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Sulfides: 1062
    - CJ 13610: 3

Experts

1.	Angioni, Carlo: 1 article (01/2021)
2.	Geisslinger, Gerd: 1 article (01/2021)
3.	Grösch, Sabine: 1 article (01/2021)
4.	Göbel, Tamara: 1 article (01/2021)
5.	Hofmann, Bettina: 1 article (01/2021)
6.	Kahnt, Astrid S: 1 article (01/2021)
7.	Maier, Thorsten J: 1 article (01/2021)
8.	Roos, Jessica: 1 article (01/2021)
9.	Rörsch, Florian: 1 article (01/2021)
10.	Steinbrink, Svenja D: 1 article (01/2021)

Related Diseases

1.	Pancreatic Neoplasms (Pancreatic Cancer) 10/01/2010 - "The common 5-LO inhibitors AA-861, Rev-5901 and MK-886 induced cytotoxic and anti-proliferative effects in 5-LO-positive Capan-2 pancreatic cancer cells; BWA4C and CJ-13,610 only caused anti-proliferative effects, while zileuton failed to impair cell viability. "
2.	Lung Neoplasms (Lung Cancer) 01/01/2021 - "Here we show that the frequently used 5-LO inhibitors AA-861, BWA4C, C06, CJ-13,610 and the FDA approved compound zileuton as well as the pan-LO inhibitor nordihydroguaiaretic acid interfere with prostaglandin E2 (PGE2) release into the supernatants of cytokine-stimulated (TNFα/IL-1β) HeLa cervix carcinoma, A549 lung cancer as well as HCA-7 colon carcinoma cells with similar potencies compared to their LT inhibitory activities (IC50 values ranging from 0.1-9.1 µM). "
3.	Fibrosis (Cirrhosis) 12/01/2007 - "Separate administration of 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC-236), a selective COX-2 inhibitor, and CJ-13,610, a 5-LO inhibitor, to carbon tetrachloride-treated mice significantly reduced fibrosis as revealed by the analysis of Sirius Red-stained liver sections without affecting necroinflammation. "
4.	Carcinoma (Carcinomatosis) 01/01/2021 - "Here we show that the frequently used 5-LO inhibitors AA-861, BWA4C, C06, CJ-13,610 and the FDA approved compound zileuton as well as the pan-LO inhibitor nordihydroguaiaretic acid interfere with prostaglandin E2 (PGE2) release into the supernatants of cytokine-stimulated (TNFα/IL-1β) HeLa cervix carcinoma, A549 lung cancer as well as HCA-7 colon carcinoma cells with similar potencies compared to their LT inhibitory activities (IC50 values ranging from 0.1-9.1 µM). "

Related Drugs and Biologics

1.	zileuton (Zyflo)
2.	2,3,5- trimethyl- 6- (12- hydroxy- 5,10- dodecadiynyl)- 1,4- benzoquinone
3.	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)
4.	Cytokines
5.	Dinoprostone (PGE2)
6.	Masoprocol (Actinex)
7.	Carbon Tetrachloride (Tetrachloromethane)
8.	Benzenesulfonamides
9.	MK-886
10.	alpha- pentyl- 3- (2- quinolinylmethoxy)benzenemethanol