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PX-866

inhibitor of phosphoinositide-3-kinase signaling with antitumor activity; structure in first source
Also Known As:
acetic acid (1S,4E,10R,11R,13S,14R)-(4-diallylaminomethylene-6-hydroxy-1-methoxymethyl-10,13-dimethyl-3,7,17-trioxo-1,3,4,7,10,11,12,13,14,15,16,17-dodecahydro-2-oxa-cyclopenta(a)phenanthren-11-yl)ester
Networked: 18 relevant articles (0 outcomes, 8 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Powis, Garth: 8 articles (04/2011 - 07/2004)
2. Bowles, Daniel W: 5 articles (04/2015 - 08/2012)
3. Jimeno, Antonio: 4 articles (04/2015 - 08/2012)
4. Wipf, Peter: 4 articles (01/2009 - 07/2004)
5. Ihle, Nathan T: 4 articles (01/2009 - 07/2004)
6. Hausman, Diana F: 3 articles (09/2015 - 08/2012)
7. Hausman, Diana: 3 articles (04/2015 - 07/2014)
8. Walker, Luke: 3 articles (04/2015 - 07/2014)
9. Peterson, Scott: 3 articles (12/2014 - 08/2012)
10. Koul, Dimpy: 3 articles (04/2011 - 06/2010)

Related Diseases

1. Glioblastoma (Glioblastoma Multiforme)
2. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
3. Squamous Cell Neoplasms (Squamous Cell Cancer)
4. Neoplasms (Cancer)
5. Colonic Neoplasms (Colon Cancer)

Related Drugs and Biologics

1. Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
2. cetuximab (Erbitux)
3. docetaxel (Taxotere)
4. squamous cell of head and neck Carcinoma
5. pioglitazone (Actos)
6. PPAR gamma
7. Acetic Acid (Vinegar)
8. Transforming Growth Factor alpha (TGF-alpha)
9. Epidermal Growth Factor Receptor (EGF Receptor)
10. Platinum

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Withholding Treatment