Cyclin-Dependent Kinase 6

Cyclin-dependent kinase 6 associates with CYCLIN D and phosphorylates RETINOBLASTOMA PROTEIN during G1 PHASE of the CELL CYCLE. It helps regulate the transition to S PHASE and its kinase activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P18.

Also Known As:

CDK6 Protein; Cell Division Protein Kinase 6; PLSTIRE Protein; Cyclin Dependent Kinase 6; Protein Kinase, Cdk6; Cdk6 Protein Kinase

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein Serine-Threonine Kinases: 3588
        Proline-Directed Protein Kinases: 28
        Cyclin-Dependent Kinases: 4005
        Cyclin-Dependent Kinase 6: 129
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Cell Cycle Proteins: 807
    - Cyclin-Dependent Kinases: 4005
      - Cyclin-Dependent Kinase 6: 129
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Serine-Threonine Kinases: 3588
      - Proline-Directed Protein Kinases: 28
        Cyclin-Dependent Kinases: 4005
        Cyclin-Dependent Kinase 6: 129

human CDK6 protein

Bio-Agent Context: Research Results