Cyclin-Dependent Kinase 4

Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16.

Also Known As:

Cdk4 Cyclin-Dependent Kinase; Cdk4 Protein; Cell Division Protein Kinase 4; Cyclin D-Dependent Kinase CDK4; PSK-J3 Kinase; p34PSK-J3 Kinase; Cdk4 Cyclin Dependent Kinase; Cyclin D Dependent Kinase CDK4; Cyclin Dependent Kinase 4; Cyclin-Dependent Kinase, Cdk4; PSK J3 Kinase; Protein Kinase, Cdk4; p34PSK J3 Kinase; Cdk4 Protein Kinase

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein Serine-Threonine Kinases: 3588
        Proline-Directed Protein Kinases: 28
        Cyclin-Dependent Kinases: 4005
        Cyclin-Dependent Kinase 4: 947
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Cell Cycle Proteins: 807
    - Cyclin-Dependent Kinases: 4005
      - Cyclin-Dependent Kinase 4: 947
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Serine-Threonine Kinases: 3588
      - Proline-Directed Protein Kinases: 28
        Cyclin-Dependent Kinases: 4005
        Cyclin-Dependent Kinase 4: 947

human CDK4 protein

Bio-Agent Context: Research Results