NgR(310) Ecto-Fc protein

an IgG fusion protein that may act as a decoy receptor to block myelin inhibitor action; promotes axonal growth and recovery after spinal cord injury

Also Known As:

AA-sNgR(310)-rFc; sNgR-Fc; soluble NgR1-Fc

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Recombinant Proteins: 2754
    - Recombinant Fusion Proteins: 333
      - NgR(310) Ecto-Fc protein: 3

Experts

1.	Li, Xin: 3 articles (10/2019 - 10/2011)
2.	So, Kwok-Fai: 3 articles (10/2019 - 10/2011)
3.	Lee, Daniel H S: 2 articles (07/2013 - 10/2011)
4.	He, Hai-Wei: 1 article (10/2019)
5.	Ye, Gen: 1 article (10/2019)
6.	You, Wei: 1 article (10/2019)
7.	Yu, Bao-Qi: 1 article (10/2019)
8.	Zhang, Yue-Lin: 1 article (10/2019)
9.	Cai, Jie: 1 article (07/2013)
10.	Hu, Chun-Lin: 1 article (07/2013)

Related Diseases

1.	Stroke (Strokes) 10/01/2019 - "Therefore, sNgR-Fc is a potential novel therapy for stroke and neurodegenerative diseases, The protocols were approved by the Committee on the Use of Live Animals in Teaching and Research of the University of Hong Kong (approval No. 4560-17) in November, 2015."
2.	Optic Nerve Injuries 10/28/2011 - "Treatment with sNgR-Fc significantly reduced RGC loss at 2 and 4 weeks after the induction of ocular hypertension and also promoted RGC survival after optic nerve transection. "
3.	Neurodegenerative Diseases (Neurodegenerative Disease) 10/01/2019 - "Therefore, sNgR-Fc is a potential novel therapy for stroke and neurodegenerative diseases, The protocols were approved by the Committee on the Use of Live Animals in Teaching and Research of the University of Hong Kong (approval No. 4560-17) in November, 2015."
4.	Ocular Hypertension (Glaucoma, Suspect) 10/28/2011 - "Treatment with sNgR-Fc significantly reduced RGC loss at 2 and 4 weeks after the induction of ocular hypertension and also promoted RGC survival after optic nerve transection. "
5.	Infarction (Infarctions) 07/01/2013 - "Our results suggest that sNgR-Fc can alleviate the pathological changes of axons following cortical infarction via decreasing the activation of RhoA/JNK signaling pathways." 07/01/2013 - "The cortical infarction was induced by photothrombotic cortical injury (PCI) in Sprague-Dawley rats, after which sNgR-Fc was injected into the lateral ventricle. " 07/01/2013 - "We investigated the effect of the soluble Nogo66 receptor (sNgR-Fc) on the protection of cortical axons after cortical infarction in rats. "

Related Therapies and Procedures

1.	Therapeutics