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spiro((1,3-diazacyclopent-1-ene)-5 : 2'-(4',5'-dimethylindan)) fumarate

an antimigraine agent; structure in first source

Also Known As:

S19014

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Indenes: 4
        Indans: 7
        spiro((1,3-diazacyclopent-1-ene)-5 : 2'-(4',5'-dimethylindan)) fumarate: 1
    - Spiro Compounds: 2
      - spiro((1,3-diazacyclopent-1-ene)-5 : 2'-(4',5'-dimethylindan)) fumarate: 1
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Indenes: 4
    - Indans: 7
      - spiro((1,3-diazacyclopent-1-ene)-5 : 2'-(4',5'-dimethylindan)) fumarate: 1
- Spiro Compounds: 2
  - spiro((1,3-diazacyclopent-1-ene)-5 : 2'-(4',5'-dimethylindan)) fumarate: 1

Experts

1.	Cordi, A A: 1 article (06/2004)
2.	Heiligers, J P C: 1 article (06/2004)
3.	Kapoor, K: 1 article (06/2004)
4.	Maassen VanDenBrink, A: 1 article (06/2004)
5.	Saxena, P R: 1 article (06/2004)
6.	Vayssettes-Courchay, C: 1 article (06/2004)
7.	Verbeuren, T J: 1 article (06/2004)
8.	Villalón, C M: 1 article (06/2004)
9.	Willems, E W: 1 article (06/2004)

Related Diseases

1.

Migraine Disorders (Migraine)

06/01/2004 - "These results suggest that (i) the systemic and carotid vascular effects of S19014 are mainly mediated by alpha2-adrenoceptors, and (ii) S19014 could be effective in the treatment of migraine with an improved cardiovascular tolerance."
06/01/2004 - "Assessment of anti-migraine potential of a novel alpha-adrenoceptor agonist S19014: effects on porcine carotid and regional haemodynamics and human coronary artery."

Related Drugs and Biologics

1.	Adrenergic Receptors (Adrenergic Receptor)