|1.||Chang, Ki Churl: 3 articles (06/2004 - 05/2002)|
|2.||Yun-Choi, Hye Sook: 3 articles (06/2004 - 05/2002)|
|3.||Kang, Young Jin: 2 articles (06/2004 - 05/2002)|
|4.||Ko, Young Shin: 1 article (06/2004)|
|5.||Kim, Hyo Jung: 1 article (06/2004)|
|6.||Lee, Young Soo: 1 article (06/2004)|
|7.||Seo, Han Geuk: 1 article (06/2004)|
|8.||Park, Min Kyu: 1 article (06/2004)|
|9.||Pyo, Hyang Sam: 1 article (06/2004)|
|10.||Pyo, Mi Kyung: 1 article (01/2004)|
|1.||Septic Shock (Toxic Shock Syndrome)
05/01/2002 - "These data strongly suggest that YS 51, a positional isomer of YS 49, might be beneficial in septic shock and/or endotoxin-induced inflammatory disorders."
05/01/2002 - "A synthetic isoquinoline alkaloid, 1-(beta-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (YS 51), reduces inducible nitric oxide synthase expression and improves survival in a rodent model of endotoxic shock."
11/15/2001 - "The antithrombotic effects of YS-49 and YS-51 were also observed in both mouse acute thrombosis model and rat arterio-venous shunt (AV shunt) model. "
11/15/2001 - "The oral administration of YS-49 and YS-51 (50 or 100 mg/kg) increased the recovery rates from the acute thrombotic challenge in mice and lowered the weight of thrombus formed inside the AV shunt tube in rats."
|3.||Multiple Organ Failure (MODS)
06/01/2004 - "The effect of YS 51, a synthetic 1-(beta-naphtylmethyl)6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline alkaloid, on the expression of manganese-superoxide dismutase (Mn-SOD), an antioxidant enzyme, was examined in sheep pulmonary artery endothelial cells (SPAEC) and a human cervical carcinoma cell line (Hela). "
|2.||1- (beta- naphthylmethyl)- 6,7- dihydroxy- 1,2,3,4- tetra- hydroisoquinoline (YS 51)
|3.||Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)