Baculoviral IAP Repeat-Containing 3 Protein

A regulator of APOPTOSIS that functions as an E3 ubiquitin protein ligase. It contains three baculoviral IAP repeats in its N-terminal half, a CARD DOMAIN, and a RING finger domain at its C-terminus. It is highly expressed in fetal lung and kidney, and adult lymphoid tissues such as spleen, thymus, and peripheral blood lymphocytes. It functions in INFLAMMATION signaling, the INNATE IMMUNE RESPONSE, cell growth and proliferation, and metastasis of tumor cells.

Also Known As:

Apoptosis Inhibitor 2; BIRC3 Protein; Baculoviral IAP Repeat Containing Protein 3; Cellular Inhibitor of Apoptosis-2; Hiap-1 Protein; IAP1 Protein; Inhibitor of Apoptosis 1 Protein; Inhibitor of Apoptosis Protein 1; c-IAP2 Protein; cIAP2 Protein; Apoptosis-2 Cellular Inhibitor; Baculoviral IAP Repeat Containing 3 Protein; Cellular Inhibitor of Apoptosis 2; Hiap 1 Protein; Inhibitor 2, Apoptosis

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Ligases: 5553
    - Ubiquitin-Protein Ligase Complexes
      - Ubiquitin-Protein Ligases: 3432
        Inhibitor of Apoptosis Proteins: 717
        Baculoviral IAP Repeat-Containing 3 Protein: 53
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Apoptosis Regulatory Proteins: 2514
      - Inhibitor of Apoptosis Proteins: 717
        Baculoviral IAP Repeat-Containing 3 Protein: 53
- Peptides: 82426
  - Intracellular Signaling Peptides and Proteins: 32
    - Apoptosis Regulatory Proteins: 2514
      - Inhibitor of Apoptosis Proteins: 717
        Baculoviral IAP Repeat-Containing 3 Protein: 53

human BIRC3 protein

Bio-Agent Context: Research Results