Cyclin-Dependent Kinase Inhibitor Proteins

A group of cell cycle proteins that negatively regulate the activity of CYCLIN/CYCLIN-DEPENDENT KINASE complexes. They inhibit CELL CYCLE progression and help control CELL PROLIFERATION following GENOTOXIC STRESS as well as during CELL DIFFERENTIATION.

Also Known As:

CDKI Proteins; CIP-KIP CDKI Proteins; CIP-KIP CKI Proteins; CKI Proteins; Cyclin-Kinase Inhibitor Proteins; INK4 CDKI Proteins; INK4 CKI Proteins; Inhibitors of Cyclin-Dependent Kinase 4 Proteins; CDKI Proteins, CIP-KIP; CDKI Proteins, INK4; CIP KIP CDKI Proteins; CIP KIP CKI Proteins; CIP KIP Cyclin Dependent Kinase Inhibitors; CKI Proteins, CIP-KIP; CKI Proteins, INK4; Cyclin Dependent Kinase Inhibitor Proteins; Cyclin Kinase Inhibitor Proteins; INK4 Cyclin Dependent Kinase Inhibitors; Inhibitor Proteins, Cyclin-Kinase; Inhibitors of Cyclin Dependent Kinase 4 Proteins; CIP-KIP Cyclin-Dependent Kinase Inhibitors; INK4 Cyclin-Dependent Kinase Inhibitors

Pharmalogical Action Categories:

Protein Kinase Inhibitors

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Cell Cycle Proteins: 807
    - Cyclin-Dependent Kinase Inhibitor Proteins: 17
  - Intracellular Signaling Peptides and Proteins: 32
    - Cyclin-Dependent Kinase Inhibitor Proteins: 17
  - Neoplasm Proteins: 2
    - Tumor Suppressor Proteins: 1683
      - Cyclin-Dependent Kinase Inhibitor Proteins: 17
- Peptides: 82426
  - Intracellular Signaling Peptides and Proteins: 32
    - Cyclin-Dependent Kinase Inhibitor Proteins: 17

human CDKN2B protein

Bio-Agent Context: Research Results