|1.||Arai, S: 1 article (08/2000)|
|2.||Kawabata, J: 1 article (08/2000)|
|3.||Oyama, K: 1 article (08/2000)|
|4.||Fukushi, E: 1 article (08/2000)|
|5.||Tanabe, S: 1 article (08/2000)|
|6.||Nakajima, T: 1 article (08/2000)|
|7.||Watanabe, M: 1 article (08/2000)|
|8.||Watanabe, J: 1 article (08/2000)|
01/01/1989 - "MH134 tumor cells as well as monocytes in MH134 tumor tissues produced TNF after systemic administration of a polyalcoholized mannoglucan (MGA) from Microellobrosporia grisea as shown by the indirect immunofluorescence technique. "
01/01/1989 - "Immunohistochemical evidence for the production of tumor necrosis factor by murine MH134 tumor cells as well as monocytes in tumor lesions after systemic administration of a polyalcoholized mannoglucan from Microellobosporia grisea."
01/01/1986 - "A rapid decrease in the number of tumor cells from S180 tumors was caused by several antitumor polysaccharides including the beta (1-3)glucans lentinan and TAK-N and a mannoglucan MGA, but not by those lacking antitumor activity. "
|2.||Hepatocellular Carcinoma (Hepatoma)
02/01/1988 - "When an antitumour mannoglucan prepared from Microellobosporia grisea, MGA was administered i.v. to C3H/He mice bearing the solid MH134 hepatoma, a cytotoxic factor was induced that was detectable in the tumour homogenate by an 8 h cytolysis assay against L-929 fibroblasts. "
07/01/1988 - "The antitumor polysaccharides mannoglucan polyalcohol (MGA), lentinan, carboxymethyl-(1----3)-beta-D-linear glucan DP540 (CM-TAK) and yeast mannan induced the CF in MH134 hepatoma tissues inoculated intradermally, with MGA inducing the highest level of the CF. "
08/01/2000 - "Chemically, the sugar moiety of the polysaccharide consisted of D-glucose and D-mannose with beta-1,4-linkages in a molar ratio of 4.4:1. Since this mannoglucan is thought to be stable in our body, it would act as a remaining allergen to cause a long-lasting allergic reaction to wheat flour."
|3.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)