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diammine(7,12- bis(1- (polyethyleneglycol- 750- monomethylether- 1- yl)ethyl)- 3,8,13,17- tetramethylporphyrin- 2,18- dipropionato)platinum(II)

structure in first source

Also Known As:

PEG-HPPt

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organometallic Compounds: 64
  - Organoplatinum Compounds
    - diammine(7,12-bis(1-(polyethyleneglycol-750-monomethylether-1-yl)ethyl)-3,8,13,17-tetramethylporphyrin-2,18-dipropionato)platinum(II): 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - Tetrapyrroles: 70
        Porphyrins: 3316
        diammine(7,12-bis(1-(polyethyleneglycol-750-monomethylether-1-yl)ethyl)-3,8,13,17-tetramethylporphyrin-2,18-dipropionato)platinum(II): 1
- Fused-Ring Heterocyclic Compounds
  - 4 or More Rings Heterocyclic Compounds
    - Tetrapyrroles: 70
      - Porphyrins: 3316
        diammine(7,12-bis(1-(polyethyleneglycol-750-monomethylether-1-yl)ethyl)-3,8,13,17-tetramethylporphyrin-2,18-dipropionato)platinum(II): 1
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Tetrapyrroles: 70
    - Porphyrins: 3316
      - diammine(7,12-bis(1-(polyethyleneglycol-750-monomethylether-1-yl)ethyl)-3,8,13,17-tetramethylporphyrin-2,18-dipropionato)platinum(II): 1
Biological Factors: 2472
- Biological Pigments: 1
  - Porphyrins: 3316
    - diammine(7,12-bis(1-(polyethyleneglycol-750-monomethylether-1-yl)ethyl)-3,8,13,17-tetramethylporphyrin-2,18-dipropionato)platinum(II): 1

Experts

1.	Bernhardt, Guenther: 1 article (11/2004)
2.	Brunner, Henri: 1 article (11/2004)
3.	Knuechel, Ruth: 1 article (11/2004)
4.	Lottner, Christian: 1 article (11/2004)

Related Diseases

1.	Neoplasms (Cancer) 11/25/2004 - "Accumulation studies with 2D and spheroid cell cultures revealed that the concentration of PEG-HPPt was 1.7-times higher in J82 cancer cells than in UROtsa cells. "
2.	Urinary Bladder Neoplasms (Bladder Cancer) 11/25/2004 - "The water-soluble porphyrin-platinum complex diammine[7,12-bis[1-(polyethyleneglycol-750-monomethylether-1-yl)ethyl]-3,8,13,17-tetramethylporphyrin-2,18-dipropionato]platinum(II) (PEG-HPPt) was studied with respect to cellular accumulation, subcellular localization, behavior in 3D-cell aggregates and degree of DNA platination on the low-differentiated J82 cells, a model of invasive bladder cancer, and UROtsa, a normal urothelial cell line. "

Related Drugs and Biologics

1.	Porphyrins
2.	Platinum
3.	DNA (Deoxyribonucleic Acid)