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vinorine

was isolated from hybrid cell suspension cultures of Rauvolfia serpentina and Rhazya stricta; structure in first source

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Indole Alkaloids: 200
    - vinorine: 3
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indole Alkaloids: 200
        vinorine: 3
    - Indolizines: 3
      - Indolizidines: 2
        Indole Alkaloids: 200
        vinorine: 3

Experts

1.	Cao, Yi: 1 article (02/2018)
2.	Gou, Haixin: 1 article (02/2018)
3.	Guo, Dongdong: 1 article (02/2018)
4.	Lu, Xingang: 1 article (02/2018)
5.	Luo, Xingjing: 1 article (02/2018)
6.	Wang, Zhiqian: 1 article (02/2018)
7.	Xu, Xiaoli: 1 article (02/2018)
8.	Ali, Hapipah Mohd: 1 article (01/2015)
9.	Basiri, Alireza: 1 article (01/2015)
10.	Fadaeinasab, Mehran: 1 article (01/2015)

Related Diseases

1.	Crush Injuries 02/01/2018 - "In this study, the effect of vinorine injection (7.5, 15 and 30 mg/kg) on motor function, sensation and nerve regeneration in sciatic nerve crush injury rat was investigated. " 02/01/2018 - "In conclusion, vinorine treatment accelerated the sciatic nerve regeneration, motor function recovery and sensation recovery after crush injury via regulation of NGF and ERK activity. "
2.	Neoplasms (Cancer) 02/01/2018 - "Growing reports exhibited the numerous pharmacology activities of vinorine such as anti-inflammation, anti-bacterial and anti-tumor. " 04/08/2005 - "Vinorine synthase belongs to the benzylalcohol acetyl-, anthocyanin-O-hydroxy-cinnamoyl-, anthranilate-N-hydroxy-cinnamoyl/benzoyl-, deacetylvindoline acetyltransferase (BAHD) enzyme superfamily, members of which are involved in the biosynthesis of several important drugs, such as morphine, Taxol, or vindoline, a precursor of the anti-cancer drugs vincaleucoblastine and vincristine. "
3.	Inflammation (Inflammations) 02/01/2018 - "Growing reports exhibited the numerous pharmacology activities of vinorine such as anti-inflammation, anti-bacterial and anti-tumor. "
4.	Brain Diseases (Brain Disorder) 01/01/2015 - "Plants from the Apocynaceae family have been traditionally used in the treatment of age-related brain disorders Methods and Results: Two new indole alkaloids, rauvolfine C (1) and 3-methyl-10,11-dimethoxy-6-methoxycarbonyl-β-carboline (2), along with five known, macusine B (3), vinorine (4), undulifoline (5), isoresrpiline (6) and rescinnamine (7) were isolated from the bark of Rauvolfia reflexa. "

Related Drugs and Biologics

1.	Indole Alkaloids
2.	Nerve Growth Factor (NGF)
3.	Paclitaxel (Taxol)
4.	Vincristine (Oncovin)
5.	Morphine (MS Contin)
6.	Enzymes
7.	Anthocyanins (Anthocyanin)
8.	Acetyltransferases
9.	rescinnamine (Moderil)
10.	anthranilic acid (anthranilate)