human CFH protein

RefSeq NM_000186

Also Known As:

CFH protein, human; Human Factor H; complement factor H protein, human; complement factor H, human

Networked: 10 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Beta-Globulins: 159
        Complement Factor H: 1229
        human CFH protein: 10
    - Immunoproteins: 43
      - Complement System Proteins: 33379
        Complement Inactivator Proteins
        Complement C3b Inactivator Proteins
        Complement Factor H: 1229
        human CFH protein: 10
  - Globulins: 3062
    - Serum Globulins: 553
      - Beta-Globulins: 159
        Complement Factor H: 1229
        human CFH protein: 10

Experts

1.	Deghmane, Ala-Eddine: 2 articles (01/2016 - 01/2016)
2.	Hong, Eva: 2 articles (01/2016 - 01/2016)
3.	Taha, Muhamed-Kheir: 2 articles (01/2016 - 01/2016)
4.	Zipfel, Peter F: 2 articles (01/2013 - 12/2002)
5.	Abramczyk, Dariusz: 1 article (01/2021)
6.	Barlow, Paul N: 1 article (01/2021)
7.	Denton, Harriet: 1 article (01/2021)
8.	Herbert, Andrew P: 1 article (01/2021)
9.	Kerr, Heather: 1 article (01/2021)
10.	Lomax-Browne, Hannah: 1 article (01/2021)

Related Diseases

1.	Macular Degeneration (Age-Related Maculopathy) 01/01/2021 - "Recombinant human factor H (hFH) has potential for treating diseases linked to aberrant complement regulation including C3 glomerulopathy (C3G) and dry age-related macular degeneration. " 09/01/2019 - "Complement factor H‑related 3 (CFHR3) belongs to the human factor H protein family and is associated with various human diseases, including nephropathy, age‑related macular degeneration and atypical hemolytic uremic syndrome. "
2.	Infections 01/01/2016 - "We used experimental intraperitoneal infection in 8-week-old transgenic female mice expressing human transferrin and human factor H. " 01/01/2016 - "Treatment with human factor H did not attenuate disease scores, serum pro-inflammatory cytokines, or vascular permeability and did not significantly affect C3 and C3a production at 26 h post-infection. "
3.	Atypical Hemolytic Uremic Syndrome 09/01/2019 - "Complement factor H‑related 3 (CFHR3) belongs to the human factor H protein family and is associated with various human diseases, including nephropathy, age‑related macular degeneration and atypical hemolytic uremic syndrome. "
4.	Sepsis (Septicemia) 01/01/2016 - "Therefore, we conclude that inhibition of the alternative complement pathway by exogenous human factor H fails to attenuate inflammation and vascular leakage at a clinically relevant intervention time point in pneumococcal sepsis in mice. " 01/01/2016 - "We assessed the effect of inhibition of the alternative pathway on sepsis associated inflammation and disease severity using human factor H treatment in a clinically relevant mice model of pneumococcal sepsis. "
5.	Bacteremia 02/01/2012 - "Enhanced bacteremia in human factor H transgenic rats infected by Neisseria meningitidis."

Related Drugs and Biologics

1.	Complement System Proteins (Complement)
2.	Proteins (Proteins, Gene)
3.	Complement Factor H (Factor H)
4.	Cytokines
5.	Transferrin (beta 2 Transferrin)
6.	Carrier Proteins (Binding Protein)