MLD 987

an NSAID for inhalation therapy of asthma; structure in first source

Also Known As:

17-allyl-1,14-dihydroxy-12-(3-(3-methoxy-4-(4-methoxycarbonylmethylphenylenecarbamoyloxy)cyclohexyl)-1-methylvinyl)-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo(22.3.1.0(4,9))octacos-18-ene-2,3,10,16-tetraone; MLD-987; MLD987

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - Macrolides: 4391
    - Tacrolimus: 7819
      - MLD 987: 2

Experts

1.	Fozard, John R: 2 articles (09/2004 - 07/2003)
2.	Mazzoni, Lazzaro: 2 articles (09/2004 - 07/2003)
3.	Buchheit, Karl-Heinz: 1 article (09/2004)
4.	Cammisuli, Salvatore: 1 article (09/2004)
5.	Enz, Albert: 1 article (09/2004)
6.	Hersperger, Rene: 1 article (09/2004)
7.	Lohse, Olivier: 1 article (09/2004)
8.	Ponelle, Monique: 1 article (09/2004)
9.	Schuler, Walter: 1 article (09/2004)
10.	Schweitzer, Alain: 1 article (09/2004)

Related Diseases

1.	Inflammation (Inflammations) 07/01/2003 - "25 and 1 h prior to OA challenge) induced reductions in the BAL fluid parameters of inflammation; IMM125 and MLD987, at a dose of 1 mg kg(-1) had no significant effect whereas SAR943 reduced lymphocyte numbers. "
2.	Asthma (Bronchial Asthma) 09/23/2004 - "Herein, we describe the design, synthesis, and evaluation in models of allergic asthma of a locally active T-cell modulator, MLD987 (1). " 09/23/2004 - "A locally active antiinflammatory macrolide (MLD987) for inhalation therapy of asthma."

Related Drugs and Biologics

1.	Macrolides
2.	SAR943

Related Therapies and Procedures

1.	Respiratory Therapy (Therapy, Respiratory)

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