Conotoxins

Peptide neurotoxins from the marine fish-hunting snails of the genus CONUS. They contain 13 to 29 amino acids which are strongly basic and are highly cross-linked by disulfide bonds. There are three types of conotoxins, omega-, alpha-, and mu-. OMEGA-CONOTOXINS inhibit voltage-activated entry of calcium into the presynaptic membrane and therefore the release of ACETYLCHOLINE. Alpha-conotoxins inhibit the postsynaptic acetylcholine receptor. Mu-conotoxins prevent the generation of muscle action potentials. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)

Also Known As:

Conotoxin; alpha-Conotoxin; mu-Conotoxin; alpha Conotoxin; alpha Conotoxins; mu Conotoxin; mu Conotoxins; alpha-Conotoxins; mu-Conotoxins

Pharmalogical Action Categories:

Calcium Channel Blockers
Neurotoxins

Complex Mixtures: 1906
- Venoms: 4328
  - Mollusk Venoms: 21
    - Conotoxins: 172
Biological Factors: 2472
- Biological Toxins: 20
  - Venoms: 4328
    - Mollusk Venoms: 21
      - Conotoxins: 172
  - Marine Toxins: 124
    - Mollusk Venoms: 21
      - Conotoxins: 172

alphaA-conotoxin OIVA

Bio-Agent Context: Research Results