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amphotericin B-arabinogalactan conjugate
Also Known As:
AMB-AG conjugate
Networked:
2
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Lactones: 1549
Polyketides: 231
Macrolides: 4391
Amphotericin B: 6619
amphotericin B-arabinogalactan conjugate: 2
Carbohydrates: 22023
Polysaccharides: 15383
Galactans: 56
amphotericin B-arabinogalactan conjugate: 2
Experts
1.
Domb, Abraham J
: 1 article (09/2004)
2.
Falk, Rama
: 1 article (09/2004)
3.
Grunwald, Jacob
: 1 article (09/2004)
4.
Hoffman, Amnon
: 1 article (09/2004)
5.
Polacheck, Itzhack
: 1 article (09/2004)
Related Diseases
1.
Aspergillosis
09/01/2004 - "
These differences included extended persistence of drug in the body and its accumulation in the lungs; thus, the AMB-AG conjugate was highly effective in treating systemic murine aspergillosis.
"
09/01/2004 - "
Distribution of amphotericin B-arabinogalactan conjugate in mouse tissue and its therapeutic efficacy against murine aspergillosis.
"
2.
Mycoses (Diseases, Fungus)
08/01/1999 - "
The overall results suggest that after further development of the AmB-AG conjugate, it may be a potent agent in the treatment of fungal infections.
"
3.
Body Weight (Weight, Body)
08/01/1999 - "
It was the least toxic AmB-AG conjugate among those tested with mice (maximal tolerated dose, 50 mg/kg of body weight), and histopathology indicated no damage to the liver or kidneys.
"