|1.||Nakao, Yoichi: 2 articles (12/2012 - 08/2004)|
|2.||Kimura, Junji: 2 articles (12/2012 - 08/2004)|
|3.||Negishi, Takayuki: 1 article (12/2012)|
|4.||Tashiro, Tomoko: 1 article (12/2012)|
|5.||Umehara, Masahiro: 1 article (12/2012)|
|6.||Takada, Yuuki: 1 article (08/2004)|
|7.||Yoshida, Wesley Y: 1 article (08/2004)|
|8.||Mooberry, Susan L: 1 article (08/2004)|
|9.||Yang, Liu: 1 article (08/2004)|
|10.||Scheuer, Paul J: 1 article (08/2004)|
12/15/2012 - "This study demonstrated that the cyclization of depsipeptide and the chirality of the 21 position in Ala in kulokekahilide-2 were important for its cytotoxic property and that addition of halogen at the para position of phenyl group in the 24-D-MePhe in kulokekahilide-2 as well as some derivatives remarkably increased their cytotoxicity in human cancer cells. "
12/15/2012 - "These results suggest that the modifications of 24-D-MePhe in kulokekahilide-2, preserving its cyclization and the chirality at the 21-position, are promising strategy for exploring new derivative of kulokekahilide-2 as anti-tumor drug."
12/15/2012 - "Kulokekahilide-2, a 26-membered cyclodepsipeptide, was isolated from Hawaiian marine mollusk and possessed potent cytotoxicity in mammalian tumor cells. "
12/15/2012 - "In the present study, we synthesized kulokekahilide-2 and its derivatives and examined the structure-activity relationships of these peptides in human cancer cells (A549, K562, and MCF7 cells). "
08/01/2004 - "Kulokekahilide-2 showed potent cytotoxicity against several cell lines (P388, SK-OV-3, MDA-MB-435, and A-10 with IC50 values ranging from 4.2 to 59.1 nM) indicating cancer cell selectivity."
|2.||antineoplaston A10 (A 10)