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nonaarginine

Also Known As:

Arg(9) peptide; nona-D-arginine; nona-L-arginine

Networked: 6 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - nonaarginine: 6

Experts

1.	Brock, Roland: 2 articles (06/2021 - 06/2018)
2.	Hobden, Jeffery A: 2 articles (11/2010 - 01/2009)
3.	Karicherla, Priyanka: 2 articles (11/2010 - 01/2009)
4.	Collado Camps, Estel: 1 article (06/2021)
5.	Dijkgraaf, Ingrid: 1 article (06/2021)
6.	Frielink, Cathelijne: 1 article (06/2021)
7.	Gotthardt, Martin: 1 article (06/2021)
8.	Lankhof, Jordi: 1 article (06/2021)
9.	van Lith, Sanne A M: 1 article (06/2021)
10.	Massuger, Leon: 1 article (06/2018)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2013 - "Thus, the current study examined the feasibility of designing and utilizing a peptide, termed 599, consisting of a synthetic influenza virus-derived endosome-disruptive fusogenic peptide sequence and a stretch of cationic cell-penetrating nona(D-arginine) residues, to deliver siRNAs into oral cancer cells and induce silencing of the therapeutic target, CIP2A, an oncoprotein overexpressed in various human malignancies including oral cancer. " 06/23/2021 - "For nonaarginine and penetratin we compared the competition of EGF binding and performance of L- and D-peptide stereoisomers, and tested the D-peptide conjugates in tumor cell spheroids and in vivo. " 06/01/2018 - "In primary tumor cultures, in contrast to nonaarginine, the amphipathic CPP penetratin was strongly sequestered by cell debris and matrix components pointing towards arginine-rich CPPs as a preferred choice. "
2.	Toxemia 08/27/2004 - "Length and terminal modification studies showed that the most potent D-polyarginine tested was nona-D-arginine (D9R) amide with a K(i) of 1.3 nm. D9R amide was shown to protect RAW264.7 cells against anthrax toxemia with an IC(50) of 3.7 microm. "
3.	Mouth Neoplasms (Oral Cancer) 01/01/2013 - "Thus, the current study examined the feasibility of designing and utilizing a peptide, termed 599, consisting of a synthetic influenza virus-derived endosome-disruptive fusogenic peptide sequence and a stretch of cationic cell-penetrating nona(D-arginine) residues, to deliver siRNAs into oral cancer cells and induce silencing of the therapeutic target, CIP2A, an oncoprotein overexpressed in various human malignancies including oral cancer. "
4.	Anthrax 08/27/2004 - "Length and terminal modification studies showed that the most potent D-polyarginine tested was nona-D-arginine (D9R) amide with a K(i) of 1.3 nm. D9R amide was shown to protect RAW264.7 cells against anthrax toxemia with an IC(50) of 3.7 microm. "
5.	Keratitis 01/01/2009 - "Nona-D-arginine therapy for Pseudomonas aeruginosa keratitis."

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Amides
3.	Oncogene Proteins (Oncogene Protein)
4.	polyarginine
5.	penetratin
6.	Interleukins
7.	Epidermal Growth Factor (EGF)
8.	Arginine (L-Arginine)
9.	6-chloro-2-(1-piperazinyl)pyrazine (CPP)

Related Therapies and Procedures

1.	Therapeutics