2- (4'- methoxybiphenyl- 4- sulfonylamino)- 3- methylbutyric acid

structure in first source

Also Known As:

(11C)MSMA

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Sulfonamides: 2809
    - 2-(4'-methoxybiphenyl-4-sulfonylamino)-3-methylbutyric acid: 1
- Sulfur Compounds: 278
  - Sulfones: 534
    - Sulfonamides: 2809
      - 2-(4'-methoxybiphenyl-4-sulfonylamino)-3-methylbutyric acid: 1
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Branched-Chain Amino Acids: 2289
    - Valine: 1999
      - 2-(4'-methoxybiphenyl-4-sulfonylamino)-3-methylbutyric acid: 1
  - Essential Amino Acids: 1152
    - Valine: 1999
      - 2-(4'-methoxybiphenyl-4-sulfonylamino)-3-methylbutyric acid: 1

Experts

1.	Baity, Winston L: 1 article (01/2004)
2.	Fei, Xiangshu: 1 article (01/2004)
3.	Gay, Dawn J: 1 article (01/2004)
4.	Hutchins, Gary D: 1 article (01/2004)
5.	Liu, Xuan: 1 article (01/2004)
6.	Martinez, Tanya D: 1 article (01/2004)
7.	Miller, Kathy D: 1 article (01/2004)
8.	Sledge, George W: 1 article (01/2004)
9.	Stone, K Lee: 1 article (01/2004)
10.	Wang, Ji Quan: 1 article (01/2004)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2004 - "From our results, we concluded that both [11C]MSMA and [11C]CGS 25966 might be unsuitable as PET tracers for cancer imaging." 01/01/2004 - "The results showed the uptakes of [11C]MSMA and [11C]CGS 25966 in these tumors were 0.95 and 0.42%dose/g in MCF-7's transfected with IL-1alpha implanted mice, 0.98 and 1.53%dose/g in MDA-MB-435 implanted mice, respectively; the ratios of tumor/muscle (T/M) and tumor/blood (T/B) were 1.21 and 1.09 (T/M, MCF-7's), 0.99 and 0.84 (T/B, MCF-7's), 1.38 and 1.27 (T/M, MDA-MB-435), 1.27 and 1.95 (T/B, MDA-MB-435), respectively. " 01/01/2004 - "The micro-PET images of [11C]MSMA and [11C]CGS 25966 in both breast cancer athymic mice were acquired for 15 min from a MCF-7's transfected with IL-1alpha and/or MDA-MB-435 implanted mouse at 45 min post iv injection of 1 mCi of the tracer using a dedicated high resolution (<3 mm full-width at half-maximum) small FOV (field-of-view) PET imaging system, Indy-PET II scanner, developed in our laboratory, which showed both tumors were invisible with both tracers. "
2.	Breast Neoplasms (Breast Cancer) 01/01/2004 - "The biodistribution of [11C]MSMA and [11C]CGS 25966 were determined at 45 min post iv injection in breast cancer animal models MCF-7's transfected with IL-1alpha implanted athymic mice and MDA-MB-435 implanted athymic mice. " 01/01/2004 - "The micro-PET images of [11C]MSMA and [11C]CGS 25966 in both breast cancer athymic mice were acquired for 15 min from a MCF-7's transfected with IL-1alpha and/or MDA-MB-435 implanted mouse at 45 min post iv injection of 1 mCi of the tracer using a dedicated high resolution (<3 mm full-width at half-maximum) small FOV (field-of-view) PET imaging system, Indy-PET II scanner, developed in our laboratory, which showed both tumors were invisible with both tracers. "

Related Drugs and Biologics

1.	N- hydroxy- 2- (((4'- methoxyphenyl)sulfonyl)benzylamino)- 3- methylbutanamide