EP1873

a small-molecule fibrin-binding gadolinium-labeled peptide derivative for noninvasive in vivo MRI of acute and subacute thrombosis after plaque rupture in an animal model of atherosclerosis

Also Known As:

EP-1873

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - EP1873: 1

Experts

1.	Barrett, John A: 1 article (04/2004)
2.	Botnar, René M: 1 article (04/2004)
3.	Graham, Philip B: 1 article (04/2004)
4.	Hamilton, James: 1 article (04/2004)
5.	Johnstone, Michael T: 1 article (04/2004)
6.	Kolodziej, Andrew: 1 article (04/2004)
7.	Laredo, James: 1 article (04/2004)
8.	Manning, Warren J: 1 article (04/2004)
9.	Parsons, Edward C: 1 article (04/2004)
10.	Perez, Alexandra S: 1 article (04/2004)

Related Diseases

1.	Thrombosis (Thrombus) 04/27/2004 - "Nine rabbits (60%) developed plaque rupture and thrombus, including 25 thrombi visually apparent on MRI as "hot spots" after injection of EP-1873. " 04/27/2004 - "We sought to test the feasibility of direct imaging of acute and subacute thrombosis using MRI together with a novel fibrin-binding gadolinium-labeled peptide, EP-1873, in an experimental animal model of plaque rupture and thrombosis. "
2.	Rupture 04/27/2004 - "Nine rabbits (60%) developed plaque rupture and thrombus, including 25 thrombi visually apparent on MRI as "hot spots" after injection of EP-1873. " 04/27/2004 - "We sought to test the feasibility of direct imaging of acute and subacute thrombosis using MRI together with a novel fibrin-binding gadolinium-labeled peptide, EP-1873, in an experimental animal model of plaque rupture and thrombosis. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Gadolinium
3.	Fibrin