|1.||Kong, Dexin: 3 articles (01/2011 - 04/2004)|
|2.||Kobayashi, Motomasa: 3 articles (01/2011 - 04/2004)|
|3.||Aoki, Shunji: 2 articles (01/2008 - 04/2004)|
|4.||Duan, Hongquan: 1 article (01/2011)|
|5.||Yamori, Takao: 1 article (01/2011)|
|6.||Sowa, Yoshihiro: 1 article (01/2008)|
|7.||Sakai, Toshiyuki: 1 article (01/2008)|
|8.||Matsui, Kouhei: 1 article (04/2004)|
01/01/2011 - "We previously reported that smenospongine, a sesquiterpene aminoquinone isolated from the marine sponge Dactylospongia elegans, showed antiproliferative or cytotoxic activities on leukemia cells. "
01/01/2008 - "Smenospongine, a sesquiterpene aminoquinone from a marine sponge, induces G1 arrest or apoptosis in different leukemia cells."
01/01/2008 - "In this study, we investigated the effect of smenospongine on the cell cycles of other leukemia cells, including HL60 human acute promyelocytic leukemia cells and U937 human histiocytic lymphoma cells by flow cytometric analysis. "
|2.||Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell)
|3.||Acute Promyelocytic Leukemia
01/01/2011 - "In this study, we investigated the effect of smenospongine on solid tumors. "
01/01/2011 - "In conclusion, smenospongine exhibits antitumor activity on solid tumors via two mechanisms, an antiangiogenic effect on endothelial cells and direct inhibition of growth of tumor cells."
01/01/2011 - "Smenospongine inhibited the growth of 39 human solid cancer cells in vitro, with a mean Log GI(50) value of -5.55. "
01/01/2011 - "Moreover, the inhibitory activity of smenospongine on growth of solid tumor cells was investigated. "
01/01/2011 - "Since angiogenesis is well known to be closely involved in growth and metastasis of solid tumors, the antiangiogenic effect of smenospongine was determined. "
|5.||BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/01/2008 - "Smenospongine, a sesquiterpene aminoquinone isolated from the marine sponge Dactylospongia elegans, was previously reported by us to induce erythroid differentiation and G1 phase arrest of K562 chronic myelogenous leukemia cells. "
04/01/2004 - "The differentiation of K562 chronic myelogenous leukemia (CML) cells by smenospongine, which is a sesquiterpene aminoquinone isolated from a marine sponge, was examined. "