|1.||Fiorillo, Marco: 2 articles (09/2015 - 06/2015)|
|2.||De Luca, Arianna: 2 articles (09/2015 - 06/2015)|
|3.||Pezzi, Vincenzo: 2 articles (09/2015 - 06/2015)|
|4.||Sotgia, Federica: 2 articles (09/2015 - 06/2015)|
|5.||Lisanti, Michael P: 2 articles (09/2015 - 06/2015)|
|6.||Cappello, Anna Rita: 2 articles (09/2015 - 06/2015)|
|7.||Avena, Paola: 1 article (09/2015)|
|8.||Du, Jun: 1 article (09/2015)|
|9.||Lu, Lin-Lin: 1 article (09/2015)|
|10.||Yang, Xiang-Ling: 1 article (09/2015)|
|1.||Breast Neoplasms (Breast Cancer)
09/28/2007 - "We suggest that treatment with XCT790 could thus enhance the efficacy of ICI182,780 in ER alpha-dependent pathologies such as breast cancer."
10/18/2011 - "Importantly, this signature also predicted the ability of an ERRα antagonist, XCT790, to inhibit proliferation in cellular models of breast cancer. "
06/15/2015 - "Secondly, the inhibition of ERRα by treatment of MC4-L2 human breast cancer cells with XCT790 (inverse agonist ligand of ERRα) before injection into the animals not only increased LDH-B expression in the tumour, but also decreased MCT1 expression in the CX group in comparison to the C group. "
|2.||Contagious Ecthyma (Orf)
11/01/2009 - "In this study, we aim to clone the ORF sequence of pig ERR alpha with touch down-PCR, analyze the expression pattern of ERR alpha protein and its subcellular localization with Western blotting and cell immunofluorescence method respectively, and identify the effect of ERR alpha on lipid accumulation in mature porcine adipocytes with its specific inhibitor XCT790. "
|3.||Adrenal Cortex Neoplasms (Adrenocortical Cancer)
06/20/2015 - "Interestingly, our results directly demonstrate that XCT790 efficiently blocks both the survival and propagation of tumor initiating stem-like cells (TICs), using the MCF7 cell line as a model system. "
10/07/2009 - "Estrogen-related receptor alpha (ERRalpha) inverse agonist XCT-790 induces cell death in chemotherapeutic resistant cancer cells."
09/22/2015 - "In MDA-MB-231 tumor xenograft models, XCT-790 decreases the expression of FN, inhibits the growth and lung metastasis, and suppresses the EMT. "
10/01/2009 - "Finally, the overexpression of PGC-1alpha sensitizes breast and colon cancer cells to growth inhibition by 5'-DFUR presumably by inducing apoptosis in tumor cells and XCT790 can inhibit the process. "
05/01/2011 - "Moreover, we showed that ERRα and VEGF knockdown by small interfering RNA or an inverse agonist of ERRα, XCT 790, could suppress cell growth compared with control cells in cervical cancer. "
|1.||ERRalpha estrogen-related receptor
|2.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|3.||Small Interfering RNA (siRNA)
|4.||Protein Isoforms (Isoforms)
|5.||Reactive Oxygen Species (Oxygen Radicals)
|6.||Messenger RNA (mRNA)
|7.||lactate dehydrogenase 1 (LDH1)
|1.||Heterologous Transplantation (Xenotransplantation)