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FR901512

a HMG-CoA reductase inhibitor produced by an agonomycetous fungus No. 14919. II.; structure in first source

Also Known As:

FR 901512

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Tetrahydronaphthalenes: 1
        FR901512: 1
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Tetrahydronaphthalenes: 1
      - FR901512: 1

Experts

1.	Fujii, Takashi: 1 article (06/2004)
2.	Hatori, Hidetaka: 1 article (06/2004)
3.	Hino, Motohiro: 1 article (06/2004)
4.	Sato, Bunji: 1 article (06/2004)
5.	Sato, Ikuko: 1 article (06/2004)
6.	Shibata, Toshihiro: 1 article (06/2004)
7.	Ueda, Hirotsugu: 1 article (06/2004)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 06/01/2004 - "FR901512 inhibited cholesterol synthesis from [14C] acetate in Hep G2 cells with an IC50 of 1.0 nM. An increase of cell surface LDL receptors observed on the FR901512 treated human hepatoma cell line Hep G2 cells. "

Related Drugs and Biologics

1.	LDL Receptors (LDL Receptor)
2.	Cholesterol
3.	Acetates (Acetic Acid Esters)