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N- (4- (3- chloro- 4- (2- pyridinylmethoxy)anilino)- 3- cyano- 7- ethoxy- 6- quinolyl)- 4- (dimethylamino)- 2- butenamide

an orally active, irreversible inhibitor of the HER-2 tyrosine kinase
Also Known As:
HKI 272; HKI-272; HKI272; neratinib
Networked: 51 relevant articles (9 outcomes, 18 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Shapiro, Geoffrey I: 6 articles (01/2014 - 05/2006)
2. Abbas, Richat: 5 articles (01/2014 - 04/2009)
3. Wong, Kwok-Kin: 5 articles (08/2007 - 05/2006)
4. Shimamura, Takeshi: 4 articles (07/2007 - 05/2006)
5. Ji, Hongbin: 4 articles (07/2007 - 05/2006)
6. Chen, Liang: 3 articles (10/2015 - 06/2006)
7. Awada, Ahmad: 3 articles (12/2013 - 03/2010)
8. Vermette, Jennifer: 3 articles (12/2013 - 04/2009)
9. Settleman, Jeffrey: 3 articles (08/2012 - 05/2005)
10. Zacharchuk, Charles: 3 articles (06/2010 - 04/2009)

Related Diseases

1. Neoplasms (Cancer)
2. Breast Neoplasms (Breast Cancer)
3. Carcinosarcoma
4. Lung Neoplasms (Lung Cancer)
5. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)

Related Drugs and Biologics

1. trastuzumab (Herceptin)
2. capecitabine (Xeloda)
3. Epidermal Growth Factor Receptor (EGF Receptor)
4. lapatinib (GW572016)
5. gefitinib (Iressa)
6. Paclitaxel (Taxol)
7. erlotinib (CP 358,774)
8. taxane
9. vinorelbine (Navelbine)
10. Epidermal Growth Factor (EGF)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)
3. Aftercare (After-Treatment)