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cyclic citrullinated peptide

a synthetic peptide that functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis
Also Known As:
CCP peptide
Networked: 542 relevant articles (9 outcomes, 59 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Huizinga, Tom W J: 9 articles (04/2013 - 01/2005)
2. Holers, V Michael: 7 articles (09/2015 - 01/2005)
3. van Schaardenburg, Dirkjan: 7 articles (01/2015 - 10/2002)
4. Huizinga, T W J: 7 articles (02/2012 - 12/2006)
5. Deane, Kevin D: 6 articles (09/2015 - 01/2005)
6. Moreland, Larry W: 6 articles (09/2015 - 09/2006)
7. Gregersen, Peter K: 6 articles (09/2013 - 12/2005)
8. Dijkmans, Ben A C: 6 articles (01/2011 - 10/2002)
9. Karlson, Elizabeth W: 6 articles (12/2010 - 06/2007)
10. van der Helm-van Mil, Annette H M: 6 articles (08/2009 - 01/2005)

Related Diseases

1. Rheumatoid Arthritis
2. Arthritis (Polyarthritis)
3. Pain (Aches)
02/01/2002 - "The developed prediction model consisted of 7 variables: symptom duration at first visit, morning stiffness for > or =1 hour, arthritis in > or =3 joints, bilateral compression pain in the metatarsophalangeal joints, rheumatoid factor positivity, anti-cyclic citrullinated peptide antibody positivity, and the presence of erosions (hands/feet). "
01/01/2007 - "However, no differences were found between the groups of patients with PsA in terms of seropositivity for rheumatoid factor and antibodies to cyclic citrullinated peptide, enthesitis, and spinal pain and stiffness. "
01/01/2006 - "Clinical indicators of persistence include symptom duration at first visit, early morning stiffness for > 1 h, arthritis in more than three joints, bilateral compression pain in metatarsophalangeal joints, rheumatoid factor positivity, anti-cyclic citrullinated peptide antibody positivity, erosions on hand or feet X-rays and a family history of rheumatoid arthritis. "
01/01/2003 - "The proposed set consists of 7 criteria: symptom duration (6 weeks - 6 months), morning stiffness of at least 1 hour, arthritis in >/= 3 joints, bilateral compression pain in the metatarsophalangeal joints, IgM-rheumatoid factor positivity, anti-cyclic-citrullinated-peptide antibody positivity and erosions on radiographs of the hands or feet. "
02/01/2012 - "Baseline HAQ score, pain, the Ritchie Articular Index (RAI), and treatment group were significant independent predictors for a HAQ score ≥ 1; the presence of rheumatoid factor (RF), anti-cyclic citrullinated peptide (anti-CCP) antibodies, and baseline radiological damage were not. "
4. Fatigue
5. Synovitis

Related Drugs and Biologics

1. Rheumatoid Factor
2. Antibodies
3. Vimentin
4. Immunoglobulin M (IgM)
5. Anti-Idiotypic Antibodies
6. ametantrone (HAQ)
7. Autoantibodies
8. Antigens
9. Immunoglobulin G (IgG)
10. Immunoglobulin A (IgA)

Related Therapies and Procedures

1. Biological Therapy
2. Kampo Medicine (Kampo)
3. Hormone Replacement Therapy (Therapy, Hormone Replacement)
4. Splenectomy
5. Plasmapheresis