HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

OPT 80

has anti-infective activity; no further info available 7/2004

Also Known As:

OPT-80; OPT80 cpd

Networked: 7 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - OPT 80: 7

Experts

1.	Czosnowski, Quinn A: 1 article (02/2012)
2.	Whitman, Craig B: 1 article (02/2012)
3.	Lancaster, Jason W: 1 article (01/2012)
4.	Matthews, S James: 1 article (01/2012)
5.	Byrne, Brendan: 1 article (01/2009)
6.	Donskey, C: 1 article (01/2009)
7.	Emery, Judy: 1 article (01/2009)
8.	Goldstein, E J C: 1 article (01/2009)
9.	Krulicki, Walter: 1 article (01/2009)
10.	Louie, T: 1 article (01/2009)

Related Diseases

1.	Clostridium Infections 01/01/2009 - "Clinical outcomes, safety, and pharmacokinetics of OPT-80 in a phase 2 trial with patients with Clostridium difficile infection." 01/01/2009 - "OPT-80, a novel, minimally absorbed macrocycle, is a candidate treatment option for Clostridium difficile infection (CDI) based on cure without recurrence of CDI in the hamster challenge model, good in vitro activity against C. " 01/01/2009 - "During a 10-day treatment for Clostridium difficile infection, OPT-80 and vancomycin were comparably effective in reducing C. " 04/01/2008 - "OPT-80, a macrocyclic antimicrobial agent for the treatment of Clostridium difficile infections: a review." 02/01/2012 - "Literature was identified through Ovid MEDLINE (1948-December 2011) and International Pharmaceutical Abstracts (1970-December 2011) using the search terms fidaxomicin, OPT-80, PAR-101, OP-118, difimicin, tiacumicin, lipiarmycin, Clostridium difficile, Clostridium difficile infection, Clostridium difficile-associated diarrhea, and cost. "
2.	Diarrhea 01/01/2012 - "Search terms included, but were not limited to, fidaxomicin, difimicin, lipiarmycin, tiacumicin B, OPT-80, Clostridium spp, and diarrhea. " 02/01/2012 - "Literature was identified through Ovid MEDLINE (1948-December 2011) and International Pharmaceutical Abstracts (1970-December 2011) using the search terms fidaxomicin, OPT-80, PAR-101, OP-118, difimicin, tiacumicin, lipiarmycin, Clostridium difficile, Clostridium difficile infection, Clostridium difficile-associated diarrhea, and cost. " 02/01/2007 - "Optimer Pharmaceuticals Inc, in collaboration with Par Pharmaceutical Companies Inc, is developing OPT-80, a narrow-spectrum macrocyclic antibiotic secreted by the actinomycete Dactylosporangium aurantiacum, for the potential treatment of Clostridium difficile-associated diarrhea (CDAD) and vancomycin-resistant Enterococcus infection. "
3.	Infections 04/01/2008 - "difficile infection, OPT-80 was considered for clinical development as a therapy for CDI. " 02/01/2007 - "Optimer Pharmaceuticals Inc, in collaboration with Par Pharmaceutical Companies Inc, is developing OPT-80, a narrow-spectrum macrocyclic antibiotic secreted by the actinomycete Dactylosporangium aurantiacum, for the potential treatment of Clostridium difficile-associated diarrhea (CDAD) and vancomycin-resistant Enterococcus infection. "

Related Drugs and Biologics

1.	Vancomycin
2.	Fidaxomicin
3.	Anti-Bacterial Agents (Antibiotics)
4.	Anti-Infective Agents (Microbicides)

Related Therapies and Procedures

1.	Therapeutics