HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

3- (N- (3,4- dimethoxybenzyl)- 2- (2- (3- methoxy- 4- (3- o- tolylureido)phenyl)acetylamino)acetamido)propanoic acid

structure in first source

Also Known As:

IVL745; XPR 1745A

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Propionates: 988
      - 3-(N-(3,4-dimethoxybenzyl)-2-(2-(3-methoxy-4-(3-o-tolylureido)phenyl)acetylamino)acetamido)propanoic acid: 3

Experts

1.	Kirkesseli, Stephane: 2 articles (10/2005 - 04/2004)
2.	Rohatagi, Shashank: 2 articles (10/2005 - 04/2004)
3.	Arshad, Hasan: 1 article (10/2005)
4.	Boyce, Malcolm: 1 article (10/2005)
5.	Choong, Lee: 1 article (10/2005)
6.	Corden, Zoe: 1 article (10/2005)
7.	Holgate, Stephen: 1 article (10/2005)
8.	Miller, Barry: 1 article (10/2005)
9.	Millet, Sylvaine: 1 article (10/2005)
10.	Norris, Virginia: 1 article (10/2005)

Related Diseases

1.	Congenital Abnormalities (Deformity) 04/01/2004 - "Embryo-fetal studies of three VLA-4 antagonists, IVL745, IVL984, and HMR1031 [Crofts et al., Birth Defects Res B 71:55-68 (this issue), 2004] with exposure on gestation days (GD) 6-17 (rat), 6-18 (rabbit) or 6-15 (mouse) showed that only IVL984 treatment resulted in embryo lethality and cardiac defects. "
2.	Asthma (Bronchial Asthma) 04/01/2004 - "IVL745 is an inhaled VLA-4 antagonist developed for the treatment of asthma. " 10/01/2005 - "In patients with mild-to-moderate atopic asthma, IVL745 did not affect the early and late response to inhaled allergen or markers of airway inflammation, except for a modest reduction in sputum eosinophils." 10/01/2005 - "Effect of IVL745, a VLA-4 antagonist, on allergen-induced bronchoconstriction in patients with asthma."
3.	Inflammation (Inflammations) 10/01/2005 - "In patients with mild-to-moderate atopic asthma, IVL745 did not affect the early and late response to inhaled allergen or markers of airway inflammation, except for a modest reduction in sputum eosinophils." 10/01/2005 - "We sought to assess the effect of IVL745, a VLA-4 antagonist, on the early and late asthmatic response (LAR) and on markers of airway inflammation after allergen inhalation. "

Related Drugs and Biologics

1.	Integrin alpha4beta1 (VLA-4)
2.	IVL 984
3.	(3S)- 3- (((2S)- 2- (4,4- dimethyl- 3- (4- ((((2- methylphenyl)amino)carbonyl)amino)benzyl)- 2,5- dioxoimidazolidin- 1- yl)- 4- methylpentanoyl)amino)- 3- phenylpropanoic acid
4.	Allergens