Kazal Pancreatic Trypsin Inhibitor

A secreted KAZAL MOTIF-containing serine peptidase inhibitor that inhibits TRYPSIN. It is a protein composed of 56 amino acid residues and is different in amino acid composition and physiological activity from the Kunitz bovine pancreatic trypsin inhibitor (APROTININ). It protects against the trypsin-mediated premature activation of ENZYME PRECURSORS in the PANCREAS. Mutations in the SPINK1 gene are associated with CHRONIC PANCREATITIS.

Also Known As:

Trypsin Inhibitor, Kazal Pancreatic; Inhibitor, Tumor-Associated Trypsin; Pancreatic Secretory Trypsin Inhibitor; SPINK1; Serine Peptidase Inhibitor, Kazal-Type 1; Serine Protease Inhibitor Kazal-Type 1; Trypsin Inhibitor Kazal Pancreatic; Trypsin Inhibitor, Tumor-Associated; Tumor-Associated Trypsin Inhibitor; Serine Peptidase Inhibitor, Kazal Type 1; Serine Protease Inhibitor Kazal Type 1; Trypsin Inhibitor, Tumor Associated; Tumor Associated Trypsin Inhibitor; Acidic Pancreatic Trypsin Inhibitor; Pancreatic Secretory Trypsin Inhibitor, Kazal; Pancreatic Trypsin Secretory Inhibitor, Kazal; Trypsin Inhibitor, Pancreatic Secretory

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Acute-Phase Proteins: 5159
      - Kazal Pancreatic Trypsin Inhibitor: 597
  - Secretory Proteinase Inhibitory Proteins: 234
    - Kazal Type Serine Peptidase Inhibitors
      - Kazal Pancreatic Trypsin Inhibitor: 597
- Peptides: 82426
  - Secretory Proteinase Inhibitory Proteins: 234
    - Kazal Type Serine Peptidase Inhibitors
      - Kazal Pancreatic Trypsin Inhibitor: 597

mouse Spink1 protein

Bio-Agent Context: Research Results