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N2- ((2S)- 2- (3,5- difluorophenyl)- 2- hydroxyethanoyl)- N1- ((7S)- 5- methyl- 6- oxo- 6,7- dihydro- 5H- dibenzo(b,d)azepin- 7- yl)- L- alaninamide

a gamma-secretase inhibitor
Also Known As:
LY 411,575; LY 411575; LY 450139; LY-411,575; LY-411575; LY411,575; LY411575; LY450139; N2-(2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)alaninamide; Semagacestat
Networked: 43 relevant articles (3 outcomes, 14 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Raman, Rema: 4 articles (10/2016 - 08/2008)
2. Aisen, Paul S: 4 articles (01/2015 - 08/2008)
3. Siemers, Eric: 4 articles (01/2015 - 03/2010)
4. Zhang, Peng: 3 articles (10/2021 - 01/2021)
5. Sun, Xiaoying: 3 articles (10/2016 - 07/2013)
6. Doody, Rachelle S: 3 articles (01/2015 - 07/2013)
7. Iwatsubo, Takeshi: 3 articles (01/2015 - 07/2013)
8. Mohs, Richard: 3 articles (01/2015 - 07/2013)
9. Sethuraman, Gopalan: 3 articles (01/2015 - 07/2013)
10. Dean, Robert A: 3 articles (03/2010 - 08/2008)

Related Diseases

1. Experimental Arthritis
2. Inflammation (Inflammations)
3. Hepatocellular Carcinoma (Hepatoma)
4. Alzheimer Disease (Alzheimer's Disease)
5. Disease Progression

Related Drugs and Biologics

1. Amyloid Precursor Protein Secretases (beta-Secretase)
2. Cytokines
3. signal peptide peptidase
4. solanezumab
5. Biomarkers (Surrogate Marker)
6. Titanium
7. Amyloid (Amyloid Fibrils)
8. Donepezil (Aricept)
9. theasinensin A
10. N2- ((2S)- 2- (3,5- difluorophenyl)- 2- hydroxyethanoyl)- N1- ((7S)- 5- methyl- 6- oxo- 6,7- dihydro- 5H- dibenzo(b,d)azepin- 7- yl)- L- alaninamide

Related Therapies and Procedures

1. Activities of Daily Living (ADL)
2. Therapeutics
3. Subcutaneous Injections
4. Oral Administration