a cationic lipid formulation used for delivery of genes, antisense oligonucleotides, and gene silencing nucleic acids
Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results


1. Wang, Xiaolin: 1 article (02/2014)
2. Qiao, Shizhang: 1 article (02/2014)
3. Yu, Meihua: 1 article (02/2014)
4. Yang, Jie: 1 article (02/2014)
5. Gu, Wenyi: 1 article (02/2014)
6. Hartono, Sandy B: 1 article (02/2014)
7. Yu, Chengzhong: 1 article (02/2014)
8. Strounina, Ekaterina: 1 article (02/2014)
9. Piette, Jacques: 1 article (08/2013)
10. Dubois, Philippe: 1 article (08/2013)

Related Diseases

1. Neoplasms (Cancer)
08/01/2013 - "The purpose of this study is to determine whether by the use of a suitable transfection agent, it is possible to increase the efficiency of the antisense oligonucleotide targeting E6 gene, named Ru-P-4. In a recent study, we showed that Oligofectamine transfected Ru-P-4 antisense oligonucleotide failed to inhibit efficiently the growth of cervical cancer cell line SiHa, contrarily to the Ru-P-6 antisense oligonucleotide, another sequence also targeting the E6 gene. "
03/01/2006 - "The cell activity was detected by methyl thiazolyl tetrazolium (MTT) assay to determine the most suitable concentration, then cells were transfected into HPV18 cervical cancer cells by oligofectamine. "
05/01/2010 - "Stereotactic injection of EGFR ASODN:FA-PAMAM complexes into established rat C6 intracranial gliomas resulted in greater suppression of tumor growth and longer survival time of tumor-bearing rats compared with PAMAM and oligofectamine-mediated EGFR-ASODN therapy. "
02/07/2014 - "The PEI-Fe-LPMSN delivered siRNA-PLK1 effectively into osteosarcoma cancer cells, leading to cell viability inhibition of 80%, higher compared to the 50% reduction when the same dose of siRNA was delivered by a commercial product, oligofectamine. "
08/01/2013 - "PDMAEMA-b-PMEMA base polyplexes at the optimal molar ratio of polymer nitrogen atoms to DNA phosphates (N/P), were able to deliver Ru-P-4 antisense oligonucleotide and to induce a higher growth inhibition in human cervical cancer SiHa cells, compared to other formulations based on Oligofectamine."
2. Osteosarcoma (Osteogenic Sarcoma)
3. Tongue Neoplasms (Tongue Neoplasm)
4. Glioma (Gliomas)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. Small Interfering RNA (siRNA)
2. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
3. Polymers
4. Phosphates
5. Nitrogen
6. DNA (Deoxyribonucleic Acid)
7. poly(2-(dimethylamino)ethyl methacrylate)