CFY196

composed of an Fab fragment of a humanized version of mA6 fused with a linker derived from a human immunoglobulin D hinge and a tetramerization domain derived from coiled-coil sequence of human transcription factor ATFalpha; inhibits human rhinovirus infection

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Recombinant Proteins: 2754
    - Recombinant Fusion Proteins: 333
      - CFY196: 2

Experts

1.	Weinberger, Miles: 1 article (10/2004)
2.	Fang, Fang: 1 article (01/2004)
3.	Yu, Mang: 1 article (01/2004)

Related Diseases

Infections

01/01/2004 - "This work has led to a promising drug candidate, CFY196, for prevention and treatment of HRV infections. "
01/01/2004 - "Viral receptor blockage by multivalent recombinant antibody fusion proteins: inhibiting human rhinovirus (HRV) infection with CFY196."
10/01/2004 - "A multivalent, recombinant, antibody fusion protein identified as CFY196 has high avidity for ICAM-1 and has the potential to protect against rhinovirus infection. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)