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Alchemix

structure inf first source

Also Known As:

1-(2-(N,N-bis(2-chloroethyl)amino)ethylamino)-4-(2-(N,N-(dimethyl)amino)ethylamino)-5,8-dihydroxy-9,10-anthracenedione; ZP281M

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Anthracenes: 12
        Anthrones: 12
        Anthraquinones: 788
        Alchemix: 2
- Quinones: 434
  - Anthraquinones: 788
    - Alchemix: 2
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Anthracenes: 12
    - Anthrones: 12
      - Anthraquinones: 788
        Alchemix: 2

Experts

1.	Patterson, Laurence H: 2 articles (06/2012 - 07/2003)
2.	Pors, Klaus: 2 articles (06/2012 - 07/2003)
3.	Abdallah, Qasem M A: 1 article (06/2012)
4.	Abdel-Rahman, Hamdy: 1 article (06/2012)
5.	Bingham, John P: 1 article (06/2012)
6.	Cosentino, Laura: 1 article (06/2012)
7.	Etzad, Jasarat: 1 article (06/2012)
8.	Hartley, John A: 1 article (06/2012)
9.	Helleday, Thomas: 1 article (06/2012)
10.	Johansson, Fredrik: 1 article (06/2012)

Related Diseases

1.	Ovarian Neoplasms (Ovarian Cancer) 07/01/2003 - "Alchemix: a novel alkylating anthraquinone with potent activity against anthracycline- and cisplatin-resistant ovarian cancer."
2.	Neoplasms (Cancer) 06/01/2012 - "We have explored further the mechanism of action of alchemix and investigated the effect of extending its side arm bearing the alkylating functionality with regard to DNA binding and activity against multidrug resistant cancer cells. "

Related Drugs and Biologics

1.	Anthracyclines
2.	DNA (Deoxyribonucleic Acid)
3.	Cisplatin (Platino)
4.	Anthraquinones