mouse perforin

GenBank NP035203; in the presence of calcium, perforin polymerizes into transmembrane tubules and is capable of lysing non-specifically a variety of target cells, similar to complement C9

Also Known As:

perforin, mouse; cytolysin, mouse; lymphocyte pore-forming protein, mouse; perforin protein, mouse

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Pore Forming Cytotoxic Proteins
      - mouse perforin: 2

Experts

1.	Brennan, Amelia J: 1 article (12/2014)
2.	Hagn, Magdalena: 1 article (12/2014)
3.	House, Imran G: 1 article (12/2014)
4.	Oliaro, Jane: 1 article (12/2014)
5.	Ramsbottom, Kelly M: 1 article (12/2014)
6.	Trapani, Joseph A: 1 article (12/2014)
7.	Voskoboinik, Ilia: 1 article (12/2014)
8.	Yagita, Hideo: 1 article (12/2014)
9.	Cousins, Scott W: 1 article (03/2003)
10.	Dix, Richard D: 1 article (03/2003)

Related Diseases

1.	Murine Acquired Immunodeficiency Syndrome (MAIDS) 03/01/2003 - "To test this hypothesis, we developed a quantitative competitive reverse transcription-PCR assay to measure mouse perforin mRNA levels in the splenic T lymphocytes and MCMV-inoculated eyes of normal mice or mice with MAIDS. "
2.	Neoplasms (Cancer) 12/01/2014 - "Despite the importance of mouse models in understanding the role of cytotoxic lymphocytes in immune-mediated disease and their role in cancer immune surveillance, no reliable intracellular detection method exists for mouse perforin. "

Related Drugs and Biologics

1.	Messenger RNA (mRNA)