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2- amino- 3- (3,4- dichlorobenzyloxy)- 6- fluorobicyclo(3.1.0)hexane- 2,6- dicarboxylic acid

a group II mGluR antagonist

Also Known As:

MGS 0039; MGS-0039; MGS0039

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Bridged-Ring Compounds: 1
      - Bridged Bicyclo Compounds
        2-amino-3-(3,4-dichlorobenzyloxy)-6-fluorobicyclo(3.1.0)hexane-2,6-dicarboxylic acid: 2
- Carboxylic Acids: 973
  - Acyclic Acids
    - Dicarboxylic Acids: 108
      - 2-amino-3-(3,4-dichlorobenzyloxy)-6-fluorobicyclo(3.1.0)hexane-2,6-dicarboxylic acid: 2
Polycyclic Compounds: 6
- Bridged-Ring Compounds: 1
  - Bridged Bicyclo Compounds
    - 2-amino-3-(3,4-dichlorobenzyloxy)-6-fluorobicyclo(3.1.0)hexane-2,6-dicarboxylic acid: 2

Experts

1.	Chaki, Shigeyuki: 2 articles (07/2006 - 10/2004)
2.	Shimazaki, Toshiharu: 2 articles (07/2006 - 10/2004)
3.	Ito, Akie: 1 article (07/2006)
4.	Yoshimizu, Takao: 1 article (07/2006)
5.	Iijima, Michihiko: 1 article (10/2004)

Related Diseases

1.	Anxiety Disorders (Anxiety Disorder) 07/01/2006 - "These results suggest that the blockade of mGluR2/3 with MGS0039 may be effective in the treatment of depressive and anxiety disorders."
2.	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 10/06/2004 - "We examined MGS0039's potential anti-obsessive-compulsive disorder activity, using the marble-burying behavior test as a model of obsessive-compulsive disorder. "

Related Drugs and Biologics

1.	metabotropic glutamate receptor 2