Streptomyces globisporus alpha-d-glucopyranosyl-1-phosphate thymidylyltransferase
from biosynthetic gene cluster for the enediyne antitumor antibiotic C-1027 from Streptomyces globisporus; catalyzes the first step in the biosynthesis of the 4-deoxy-4-(dimethylamino)-5,5-dimethyl-d-ribopyranose moiety by activating alpha-d-glucopyranosyl-1-phosphate (Glc-1-P) into deoxythymidine diphosphate-alpha-d-glucose; amino acid sequence in first source
Also Known As:
alpha-d-glucopyranosyl-1-phosphate thymidylyltransferase, Streptomyces globisporus; Glc-1-P-TT, S globisporus; SgcA1 protein, S globisporus
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Bio-Agent Context: Research Results