MAP Kinase Kinase 4

A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES and the RETINOID X RECEPTORS. It takes part in a SIGNAL TRANSDUCTION pathway that is activated in response to cellular stress.

Also Known As:

JN Kinase Kinase; JNK Kinase; JNK-Activating Protein Kinase; JNKK1 Protein Kinase; Jun Amino-Terminal Kinase Kinase; MEK4 Protein Kinase; Mitogen-Activated Protein Kinase Kinase 4; SAP Kinase Kinase 1; SAP Kinase-Extracellular Signal-Regulated Kinase Kinase 1; SAPK-ERK Kinase 1; SEK1 Protein Kinase; Stress-Activated Protein Kinase Kinase 1; JNK Activating Protein Kinase; Jun Amino Terminal Kinase Kinase; Kinase, JNKK1 Protein; Mitogen Activated Protein Kinase Kinase 4; Protein Kinase, JNK-Activating; Protein Kinase, JNKK1; Protein Kinase, MEK4; Protein Kinase, SEK1; SAP Kinase Extracellular Signal Regulated Kinase Kinase 1; SAPK ERK Kinase 1; Stress Activated Protein Kinase Kinase 1

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein-Tyrosine Kinases: 7697
        Mitogen-Activated Protein Kinase Kinases: 6698
        MAP Kinase Kinase 4: 75
        Protein Serine-Threonine Kinases: 3588
        Mitogen-Activated Protein Kinase Kinases: 6698
        MAP Kinase Kinase 4: 75
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein-Tyrosine Kinases: 7697
      - Mitogen-Activated Protein Kinase Kinases: 6698
        MAP Kinase Kinase 4: 75
    - Protein Serine-Threonine Kinases: 3588
      - Mitogen-Activated Protein Kinase Kinases: 6698
        MAP Kinase Kinase 4: 75

human MAP2K4 protein

Bio-Agent Context: Research Results