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topovale

topoisomerase I-targeting anticancer drug; structure in first source
Also Known As:
8,9-dimethoxy-5-(2-N,N-dimethylaminoethyl)-2,3-methylenedioxy-5H-dibenzo(c,h)(1,6)naphthyridin-6-one; ARC-111; ARC111
Networked: 6 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Rouleau, Cecile: 2 articles (05/2011 - 10/2008)
2. Bagley, Rebecca G: 2 articles (05/2011 - 10/2008)
3. Lavoie, Edmond J: 2 articles (05/2011 - 10/2008)
4. Roth, Stephanie: 2 articles (05/2011 - 10/2008)
5. Yao, Min: 2 articles (05/2011 - 10/2008)
6. Teicher, Beverly A: 2 articles (05/2011 - 10/2008)
7. Wang, Fei: 2 articles (05/2011 - 10/2008)
8. Krumbholz, Roy: 2 articles (05/2011 - 10/2008)
9. Kurtzberg, Leslie S: 2 articles (05/2011 - 10/2008)
10. Yu, Xian-Jie: 2 articles (05/2011 - 10/2008)

Related Diseases

1. Neoplasms (Cancer)
2. Anoxia (Hypoxia)
3. Wilms Tumor (Wilm's Tumor)
4. Medulloblastoma
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. Topotecan (Hycamtin)
2. irinotecan (Camptosar)
3. Type I DNA Topoisomerases (Topoisomerase I)
4. Ubiquitin
5. Nocodazole
6. Proteins (Proteins, Gene)
7. Oxygen
8. Camptothecin
9. Adenosine Triphosphate (ATP)
10. ATP dependent 26S protease (26S proteasome)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)