HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

dimanganese decacarbonyl

Also Known As:

DMDC complex; Mn2(CO)10

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Inorganic Chemicals: 9
- Manganese Compounds: 12
  - dimanganese decacarbonyl: 3

Experts

1.	Chen, Xiaoyuan: 1 article (12/2018)
2.	Cheng, Siyuan: 1 article (12/2018)
3.	Dai, Yulun: 1 article (12/2018)
4.	Fan, Wenpei: 1 article (12/2018)
5.	Jacobson, Orit: 1 article (12/2018)
6.	Lin, Lisen: 1 article (12/2018)
7.	Liu, Yijing: 1 article (12/2018)
8.	Niu, Gang: 1 article (12/2018)
9.	Shan, Lingling: 1 article (12/2018)
10.	Shao, Emily: 1 article (12/2018)

Related Diseases

1.	Neoplasms (Cancer) 12/26/2018 - "More importantly, the reducibility-activated Mo(VI)-to-Mo(V) conversion within POM not only endows the POM-anchored HMON with outstanding TME-responsive photoacoustic (PA) imaging contrast and photothermal therapy (PTT) performance but also plays an indispensable role in controllably triggering the decomposition of the Mn2(CO)10 payload for CO release, which gives rise to remarkable synergistic PTT-enhanced CO gas therapy for complete tumor eradication. " 01/01/2023 - "Meanwhile MnO2 , as the photolytic byproduct of Mn2 (CO)10 , has both glutathione (GSH) depletion and Fenton-like Mn2+ delivery properties to produce highly toxic hydroxyl radical (⋅OH) in tumors. "
2.	Theileriasis 11/22/2023 - "Site-selective C(sp3)-H functionalization of unreactive hydrocarbons is always challenging due to its inherited chemical inertness, slightly different reactivity of various C-H bonds, and intrinsically high bond dissociation energies. Here, we present a site-selective C-H alkylation of naphthoquinone with unactivated hydrocarbons using Mn2(CO)10 as a catalyst under blue-light (457 nm) irradiation without any external acid or base and pre-functionalization. The selective C-H functionalization of tertiary over secondary and secondary over primary C(sp3)-H bonds in abundant chemical feedstocks was achieved, and hydroxylation of quinones was realized in situ by employing the developed methodology. This protocol provides a new catalytic system for the direct construction of high-value-added compounds, namely, parvaquone (a commercially available drug, used to treat theileriosis) and its derivatives under ambient reaction conditions. Moreover, this operationally simple protocol applies to various linear-, branched-, and cyclo-alkanes with high degrees of site selectivity under blue-light conditions and could provide rapid and straightforward access to versatile methodologies for upgrading feedstock chemicals. "

Related Drugs and Biologics

1.	Hydroxyl Radical
2.	Quinones
3.	Naphthoquinones
4.	Hydrocarbons
5.	Glutathione (Reduced Glutathione)
6.	Alkanes
7.	Acids
8.	parvaquone (993C)

Related Therapies and Procedures

1.	Therapeutics
2.	Photothermal Therapy