FeAOX-6

antioxidant derived from a molecular combination of the chromanyl and polyisoprenyl moieties; structure in first source

Also Known As:

2,5,7,8-tetramethyl-2-2(4,8,12-trimethyltrideca-1,3,5,7,11-pentaenyl)chroman-6-ol

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromans: 3
        FeAOX-6: 3
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromans: 3
        FeAOX-6: 3

Experts

1.	Avanzi, Luca: 3 articles (06/2007 - 12/2004)
2.	Manfredini, Stefano: 3 articles (06/2007 - 12/2004)
3.	Bravo, Elena: 1 article (06/2007)
4.	Napolitano, Mariarosaria: 1 article (06/2007)
5.	Iannone, Anna: 1 article (07/2006)
6.	Palozza, Paola: 1 article (07/2006)
7.	Serini, Simona: 1 article (07/2006)
8.	Verdecchia, Sara: 1 article (07/2006)
9.	Vertuani, Silvia: 1 article (07/2006)
10.	Marazova, Katia: 1 article (12/2004)

Related Diseases

1.	Reperfusion Injury 12/01/2004 - "The aim of the present study was to estimate the capability of three novel chimeric molecules derived by assembling known antioxidant moieties, namely FeAOX-6, comprising a chromanyl head and the polyisoprenyl sequence characteristic for lycopene, FeCD-52, derived from the conjugation of ascorbic acid and a polyphenol moiety (FeRS-4) and FeDG-17, derived from the combination of ascorbic acid and a chromanyl head, to confer neuroprotection in an in vitro model of guinea-pig whole urinary bladder subjected to anoxia-glucopenia/reperfusion injury. "
2.	Hypoxia (Hypoxemia) 12/01/2004 - "The aim of the present study was to estimate the capability of three novel chimeric molecules derived by assembling known antioxidant moieties, namely FeAOX-6, comprising a chromanyl head and the polyisoprenyl sequence characteristic for lycopene, FeCD-52, derived from the conjugation of ascorbic acid and a polyphenol moiety (FeRS-4) and FeDG-17, derived from the combination of ascorbic acid and a chromanyl head, to confer neuroprotection in an in vitro model of guinea-pig whole urinary bladder subjected to anoxia-glucopenia/reperfusion injury. "
3.	Atherosclerosis 06/01/2007 - "Effects of new combinative antioxidant FeAOX-6 and alpha-tocotrienol on macrophage atherogenesis-related functions."
4.	Chronic Disease (Chronic Diseases) 07/01/2006 - "In view of these results, FeAox-6 represents a new potential preventive agent in chronic diseases in which oxidative stress plays a pathogenic role."

Related Drugs and Biologics

1.	Antioxidants
2.	Polyphenols
3.	Ascorbic Acid (Vitamin C)
4.	Lycopene
5.	alpha tocotrienol