5- carboxy- 1,1,3,3- tetramethylisoindolin- 2- yloxyl
antioxidant; structure in first source
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Bio-Agent Context: Research Results
|1. ||Lymphoma (Lymphomas)
|2. ||Ataxia Telangiectasia (Louis Bar Syndrome)
- "Three water-soluble carboxy nitroxide antioxidants, 5-carboxy-1,1,3,3-tetramethylisoindolin-2-yloxyl, 4-carboxy-2,2,6,6-tetramethylpiperidin-1-yloxyl, and 3-carboxy-2,2,5,5-tetramethylpyrrolidin-1-yloxyl, show significant impact on the postirradiation survival rates of ataxia telangiectasia (A-T) cells compared to normal cells, an assay which represents a model for understanding the impact of ROS damage on the A-T phenotype.
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