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myriadenolide

an immunosuppressive agent isolated from Alomia myriadenia; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - myriadenolide: 1

Experts

1.	Amarante-Mendes, Gustavo Pessini: 1 article (11/2003)
2.	Brumatti, Gabriela: 1 article (11/2003)
3.	Corrêa-Oliveira, Rodrigo: 1 article (11/2003)
4.	Martins-Filho, Olindo Assis: 1 article (11/2003)
5.	Souza-Fagundes, Elaine Maria: 1 article (11/2003)
6.	Zani, Carlos Leomar: 1 article (11/2003)

Related Diseases

1.	Hematologic Neoplasms (Hematological Malignancy) 11/01/2003 - "Taken together, our results indicate myriadenolide as a novel candidate for the treatment of hematological malignancies."
2.	Leukemia 11/01/2003 - "Here we show for the first time that myriadenolide has caspase-dependent cytotoxic activity against human leukemia cells from both lymphocytic (Jurkat) and monocytic (THP-1) lineages, because preincubation of Jurkat or THP-1 cells with the broad-spectrum caspase inhibitor z-VAD-fmk completely abrogated cell death. "

Related Drugs and Biologics

1.	Caspases
2.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone