|1.||Cheng, Mei: 3 articles (01/2014 - 01/2012)|
|2.||Agarwal, Rajesh: 3 articles (01/2014 - 04/2010)|
|3.||Yu, Fei: 3 articles (01/2014 - 01/2012)|
|4.||Agarwal, Chapla: 3 articles (01/2014 - 04/2010)|
|5.||Thompson, John A: 3 articles (01/2014 - 04/2010)|
|6.||Cai, Qian: 3 articles (01/2014 - 01/2012)|
|7.||Lee, Hyong Joo: 3 articles (05/2009 - 04/2008)|
|8.||Lee, Ki Won: 3 articles (05/2009 - 04/2008)|
|9.||Li, Bao-ying: 2 articles (01/2014 - 01/2012)|
|10.||Li, Xiao-li: 2 articles (01/2014 - 01/2012)|
05/15/2009 - "In this study, we investigated the HNE-induced apoptosis mechanism and the protective effects of the cocoa procyanidin fraction (CPF) and its major antioxidant procyanidin B2 against the apoptosis induced by HNE in rat pheochromocytoma (PC12) cells. "
04/02/2008 - "In this study, we investigated the possible protective effects of a cocoa procyanidin fraction (CPF) and procyanidin B2 (epicatechin-(4beta-8)-epicatechin) - a major polyphenol in cocoa - against apoptosis of PC12 rat pheochromocytoma (PC12) cells induced by hydrogen peroxide (H(2)O(2)). "
05/25/2015 - "Moreover, the toxic property of procyanidin B2 towards triple negative breast cancer cells to normal cells offers platform for pre-clinical trial and an insight to the treatment of cancer."
05/25/2015 - "Mechanisms of DNA methyltransferase-inhibitor interactions: Procyanidin B2 shows new promise for therapeutic intervention of cancer."
10/15/2005 - "As a pro-oxidant property, we examined DNA damage induced by procyanidin B2, using 32P-labeled DNA fragments obtained from genes relevant to human cancer. "
07/25/2008 - "The TPA-induced promoter activity and expression of cyclooxygenase-2, which is involved in tumor promotion and inflammation, were dose-dependently inhibited by CPF or procyanidin B2. "
04/01/2010 - "Present study assessed the influence of gallate esterification on the anti-cancer activity of procyanidin B2 (B2) in androgen-dependent human prostate carcinoma LNCaP cells employing B2-3,3'-di-O-gallate (B2-G(2)), two mono-gallate esters B2-3-O-gallate (B2-3G) and B2-3'-O-gallate (B2-3'G) and the parent compound B2, all isolated from grape seed extract (GSE). "
01/01/2014 - "Quantitative proteomics study of protective effects of grape seed procyanidin B2 on diabetic cardiomyopathy in db/db mice."
01/01/2014 - "Grape seed procyanidin B2 (GSPB2) has been known as an anti-oxidant in treating diabetes mellitus; however, little is known about its effects and underlying mechanisms on diabetic cardiomyopathy. "
|4.||Diabetic Nephropathies (Diabetic Nephropathy)
06/01/2013 - "Hence, the present study evaluated the protective effects of grape seed procyanidin B2 (GSPB2) and explored its molecular targets underlying diabetic nephropathy by a comprehensive quantitative proteomic analysis in db/db mice. "
06/01/2013 - "Proteomic analysis of kidney and protective effects of grape seed procyanidin B2 in db/db mice indicate MFG-E8 as a key molecule in the development of diabetic nephropathy."
|5.||Prostatic Neoplasms (Prostate Cancer)
01/01/2014 - "Recently, we identified procyanidin B2 3,3(″)-di-O-gallate (B2G2) as most active constituent of grape seed extract (GSE) for efficacy against prostate cancer (PCa). "
01/01/2014 - "Procyanidin B2 3,3(″)-di-O-gallate, a biologically active constituent of grape seed extract, induces apoptosis in human prostate cancer cells via targeting NF-κB, Stat3, and AP1 transcription factors."
|2.||Grape Seed Extract
|3.||Hydrogen Peroxide (Hydroperoxide)
|4.||DNA (Deoxyribonucleic Acid)
|5.||Catechin (Z 7300)
|8.||Cyclooxygenase 2 (Cyclooxygenase-2)
|10.||NF-kappa B (NF-kB)
|1.||Chinese Traditional Medicine (Traditional Chinese Medicine)