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rat PKHD1 protein

expressed in cholangiocyte cilia and disruption of Pkhd1 by a germ line mutation in the PCK rat or by siRNA in IBDUs results in abnormalities in ciliary morphology and possibly biliary cystogenesis; has been sequenced; human protein is also available
Also Known As:
PKHD1 protein, rat; fibrocystin protein, rat; polycystic kidney and hepatic disease 1 (autosomal recessive) protein, rat
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Bio-Agent Context: Research Results