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azadiradione

structure in first source

Networked: 7 relevant articles (1 outcomes, 1 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Limonins: 143
        azadiradione: 7

Experts

1.	Haldar, Saikat: 2 articles (01/2015 - 10/2013)
2.	Jana, Nihar Ranjan: 1 article (08/2018)
3.	Kumar, Shashi Shekhar: 1 article (08/2018)
4.	Kumar, Vipendra: 1 article (08/2018)
5.	Mandal, Subhash C: 1 article (08/2018)
6.	Nelson, Vinod K: 1 article (08/2018)
7.	Pal, Mahadeb: 1 article (08/2018)
8.	Singh, Brijesh Kumar: 1 article (08/2018)
9.	Vatsa, Naman: 1 article (08/2018)
10.	Barthwal, Manoj K: 1 article (06/2015)

Related Diseases

1.	Body Weight (Weight, Body) 08/01/2018 - "Prolonged treatment of azadiradione to HD mice significantly improved the progressive deterioration in body weight, motor functioning along with extension of lifespan. " 01/01/2013 - "This study was carried out to evaluate the anti-nociceptive and anti-inflammatory activities of carbon tetrachloride extract (CTCE) of Azadirachta indica fruit skin and its isolated constituent azadiradione at two different dose levels (50 and 100 mg kg⁻¹ body weight). "
2.	Huntington Disease (Huntington's Disease) 08/01/2018 - "Azadiradione Restores Protein Quality Control and Ameliorates the Disease Pathogenesis in a Mouse Model of Huntington's Disease."
3.	Neoplasms (Cancer) 10/18/2013 - "Further, utility of this protocol was illustrated on the cytotoxic activity of azadiradione derivatives against several cancer cell lines through cell imaging of two qualified fluorescent probes. " 12/01/2008 - "All limonoids (1-5) showed inhibitory effect against Plasmodium falciparum with IC(50) values ranging from 2.06 to 6.31 microg/ml. Only azadiradione (2) exhibited strong inhibitory effect against Mycobacterium tuberculosis with the MIC of 6.25 microg/ml. Compounds 1-4 also showed cytotoxic activity against NCI-H187, KB and MCF-7 cancer cell lines and dysobinine (1) had the highest activity with IC(50) of 1.67, 3.17 and 2.15 microg/ml, respectively." 04/25/2011 - "Thirty-five limonoids, including 15 of the azadiradione type (1-15), five of the gedunin type (16-20), four of the azadirachtin type (21-24), nine of the nimbin type (25-33), and two degraded limonoids (34, 35), isolated from Azadirachta indica seed extracts, were evaluated for their cytotoxic activities against five human cancer cell lines. "
4.	Stomach Ulcer (Gastric Ulcer) 06/01/2015 - "Cytoprotective and Anti-secretory Effects of Azadiradione Isolated from the Seeds of Azadirachta indica (neem) on Gastric Ulcers in Rat Models."
5.	Hyperglycemia 01/01/2015 - "Thus, the limonoids azadiradione and gedunin could bind and inactivate HPA (anti-diabetic target) and may prove to be lead drug candidates to reduce/control post-prandial hyperglycemia. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Carbon Tetrachloride (Tetrachloromethane)
3.	Limonins
4.	gedunin
5.	Fluorescent Dyes (Fluorescent Probes)
6.	azadirachtin (azadirachtin A)
7.	nimbin