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N,N-dimethylglycine 3- (5,6,7,13- tetrahydro- 9- ((1- methylethoxy)methyl)- 5- oxo- 12H- indeno(2,1- a)pyrrolo(3,4- c)carbazol- 12- yl)propyl ester

prodrug of CEP-5214, which has antineoplastic and antiangiogenic activities; inhibits VEGF-R2 tyrosine kinase; structure in first source
Also Known As:
CEP 7055; CEP-7055; CEP7055
Networked: 2 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Klein-Szanto, Andres: 2 articles (07/2006 - 09/2003)
2. Hunter, Kathryn: 2 articles (07/2006 - 09/2003)
3. Ruggeri, Bruce: 2 articles (07/2006 - 09/2003)
4. Jones-Bolin, Susan: 2 articles (07/2006 - 09/2003)
5. Zhao, Hugh: 1 article (07/2006)
6. Pritchard, Sonya: 1 article (09/2003)
7. Yang, Shi: 1 article (09/2003)
8. Herbert, Jean-Marc: 1 article (09/2003)
9. Gingrich, Diane: 1 article (09/2003)
10. Pili, Roberto: 1 article (09/2003)

Related Diseases

1. Neoplasms (Cancer)
2. Carcinoma (Carcinomatosis)
3. Glioblastoma (Glioblastoma Multiforme)
4. Neurologic Manifestations (Neurological Manifestations)
5. Hemorrhage

Related Drugs and Biologics

1. irinotecan (Camptosar)
2. temozolomide (Temodar)
3. oxaliplatin (Eloxatin)
4. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
5. Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
6. Phosphotransferases (Kinase)
7. Cytotoxins
8. 3- (5,6,7,13- tetrahydro- 9- ((1- methylethoxy)methyl)- 5- oxo- 12H- indeno(2,1- a)pyrrolo(3,4- c)carbazol- 12- yl)propanol
9. dimethylglycine

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)