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FR236924
structure in first source
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Alicyclic Hydrocarbons: 1
Cycloparaffins: 6
Cyclopropanes: 9
FR236924: 1
Acyclic Hydrocarbons
Alkanes: 241
FR236924: 1
Experts
1.
Nishizaki, Tomoyuki
: 1 article (03/2003)
2.
Tanaka, Akito
: 1 article (03/2003)
Related Diseases
1.
Dementia (Dementias)
03/24/2003 - "
The newly synthesized linoleic acid derivative, FR236924, induces a long-lasting facilitation of hippocampal neurotransmission based on a persistent enhancement in the activity of presynaptic nicotinic ACh receptors via a PKC pathway and the ensuing increase in glutamate release, not only in vitro but in vivo at a low dosage (2mg/kg, ip), which suggested the possibility of its use as a promising anti-dementia drug.
"
Related Drugs and Biologics
1.
Linoleic Acid (Linoleate)
2.
Glutamic Acid (Glutamate)
3.
Cholinergic Receptors